Final Score: San Diego 7, Cincinnati 3

Cincinnati, OH (Sports Network) - Jake Peavy struck out nine in 6 1/3 solid innings to lead San Diego over Cincinnati, 7-3, in the first of a three-game set at Great American Ball Park.

Peavy (4-1) allowed just two runs and three hits in the outing. Xavier Nady belted a two-run homer and Rondell White and Shane Victorino each drove in a pair of runs for the Padres, who have won three straight.

Peavy's pitching overshadowed the major league debut of Jeff Austin (0-1), who suffered the loss for Cincy after allowing four runs on three hits over six innings. He struck out six and walked four.

Jose Guillen and Reggie Taylor hit solo homers for the Reds, who had a brief two-game winning streak snapped.

White belted a curve ball to the wall in left field for a two-out, two-run double in the third inning, scoring Ramon Vazquez and Ryan Klesko for a 2-0 San Diego lead. Vazquez and Klesko had each drawn walks off Austin.

The Padres were retired in order in the fourth and fifth innings, but Nady's two-run homer with two outs in the sixth plated White and gave San Diego a 4-0 advantage. White, who had the only Padres hits until Nady's blast, had stroked a one-out single to reach base.

San Diego tagged Reds reliever Brian Reith for a run in the seventh when Vazquez's sacrifice fly scored Victorino, but Cincinnati got it back in the bottom of the inning when Guillen's leadoff solo homer just cleared the wall in right field, pulling the team within 5-1.

Peavy then walked Sean Casey, who moved to third on an infield single and fielder's choice. Padres manager pulled Peavy and replaced him with Mike Matthews, who promptly surrendered a first-pitch sacrifice fly to Adam Dunn, allowing the Reds to pull within 5-2.

The Padres came right back with a pair of runs in the eighth when Victorino belted a two-run double off Reith to make it a 7-2 San Diego advantage. Taylor blasted a pinch-hit homer in the home-half of the inning off Padres reliever Luther Hackman to get Cincy within 7-3, but Jesse Orosco retired the Reds in the ninth to preserve the win.

With his appearance, Orosco became just the 23rd player in major league history to play in a game at the age of 46. His birthday was on Monday.

Game Notes

This is the first meeting of the season between the teams. Cincinnati went 5-1 versus San Diego last year, winning the final five meetings...The Reds are just 5-8 at home this season, while the Padres are 5-8 on the road.

04/25 22:08:58 ET